Impact of microfluidic sperm sorting on embryo quality and comprehensive chromosome screening outcomes of couples with repeated implantation failure

  • Fecha: 3 julio, 2018
  • Revista: ESHRE 2018
  • Autores: Emre Pabuccu, Recai Pabuccu, Semra Sertyel, Dogus Demirkıran, Huseyin Gunes, Sadik Dogan, A. Hakan Haliloglu, Ozgur Sahin

What is the impact of the microfluidic sperm selection technique for IVF/ICSI on embryo quality and euploidy rates in couples with Repeated Implantation Failure (RIF)?

When microfluid chip-sorted spermatozoa is used for IVF/ICSI, a higher number of top quality blastocysts and better euploidy rates were observed compared to standard selection.

This was a retrospective analysis between 2016 and 2017. In total, data from 171 patients were obtained for the analysis that accounts for 491 embryos.

Wider implications of the findings: Successful euploid-blastocyst formation is the consequence of a perfect fertilization and mitosis. When comparable women age and number of oocytes are considered, chip sorted spermatozoas may influence results in terms of better blastocyst formation and euploidy when DFI is relatively high (>15% in both groups). Cost should be considered.